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requirement of medical materials for hemolysis experiment (<5%) .MTT assay showed that , after 4 days of culture , the optical densi-ties were 0.498 ±0.218 and 0.566 ±0.266 in the 120℃12 h and 24 h groups and 0.668 ±0.268 and 0.769 ±0.213 in the 150℃12 h and 24 h groups, while after 8 days, the optical densities were 0.767 ±0.267 and 0.836 ±0.236 in the 120℃12 h and 24 h groups and 0.765 ±0.265 and 0.903 ±0.303 in the 150℃12 h and 24 h groups, all significantly higher than in the non-CaTiO3 group at 4 (0.341 ±0.143) and 8 days (0.731 ±0.121) (P<0.05). Conclusion The CaTiO3 coating on titanium is neither mutagenic nor hemolytic and has no toxicity on osteoblasts .Instead, it can promote the proliferation of osteoblasts , and therefore is a valuable coating material for implants .
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BACKGROUND:Nano-calcium titanate, prepared with different modifiers, have properties of good osteogenesis, bone conductibility and biocompatibility. OBJECTIVE:To observe the influence of nano-calcium titanate materials on the proliferation and differentiation of osteoblasts. METHODS:Nano-calcium titanate was prepared with modifiers such as polyethylene glycol, acetyl trim ethyl ammonium bromide and sodium citrate. Meanwhile, nano-calcium titanate without modifier was prepared. Al the four kinds of nano-calcium titanate materials were used to prepare nano-calcium titanate extracts under the concentration of 0.1, 1.0, 10 g/L, respectively. The proliferation of osteoblasts was observed through 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and alkaline phosphatase activity of osteoblasts was observed. Osteoblasts cultured in normal condition served as contrast. RESULTS AND CONCLUSION:The proliferation of osteoblasts cultured in the calcium titanate extracts prepared with polyethylene glycol, acetyl trim ethyl ammonium bromide and sodium citrate and without modifier was obviously improved under the concentration of 1.0 and 10 g/L. Absorbance value of the cells cultured in the above-mentioned four kinds of calcium titanate extracts 1.0 and 10 g/L) for 3, 6, 9 days exceeded the contrast (P<0.05, P<0.01), as wel as the alkaline phosphatase activity (P<0.05, P<0.01). Calcium titanate prepared with polyethylene glycol, acetyl trim ethyl ammonium bromide and sodium citrate and without modifier has no cytotoxicity effect on osteoblasts, and can promote the proliferation and differentiation of osteoblasts.
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Objective To identify the location of medicines in combat readiness medicine cabinet.Methods RFID system was used in combination with series antennas separated in space in combat readiness medicine cabinet.Results The combat readiness medicine cabinet equipped with RFID system could identify the location of medicines in medicine cabinet.It realized the location management and automatic classification statistics for medicines without opening cabinet.It greatly shortened the time in taking medicine in field emergency care.Conclusion Intelligent medicine cabinet based on RFID technology can upgrade the modernization level of sanitation logistics and provide a modern management method for iatrical material of combat readiness of PLA.
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Objective To provide information collection,processing and inquiry system,which is safe,accurate rapid and in real time,for combat readiness medical supplies.Methods RFID technology and series antenna coils separated in space were used in combat readiness medicine-chest,thus enabling the medicine-chest to have the virtue of intelligence.Results The combat readiness medicine-chest equipped with RFID system can automatically classify to count and manage medical supplies in medicine-chest without opening the chest.The medical supplies can be monitored in real time and the information of outdated medicine can be automatically prompted.Conclusion Intelligent medicine-chest based on RFID technology can provide informatized method and technique for the management of combat readiness medical supplies for PLA.